Hydrochloric Acid → HCID 22666373, compound

Participants

Reaction Steps

In 3.0 mL of ethyl acetate is dissolved 0.62 g of N-[5-(2-benzo[b]thiophen-5-ylethoxy)pentyl]-N,N-diethylamine, to which is added 1.1 mL of 3.6 mol/L solution of dry hydrogen chloride in ethyl acetate. The mixture is stirred at ambient temperature for one hour. The reaction mixture is diluted with 5 mL of diisopropyl ether and stirred at ambient temperature for one hour. The deposited crystal is collected by filtration, washed with ethyl acetate and dried to obtain 0.55 g of N-[5-(2-benzo[b]thiophen-5-ylethoxy)pentyl]-N,N-diethylamine hydrochloride.

Provenance & Evidence