Oxalic Acid → HCID 22666325, compound

HRID 1007904Notes

Reaction equation

HRID 1007904 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]2[CH:6]=[CH:7][CH:8]=[C:9]([CH2:10][CH2:11][O:12][CH2:13][CH2:14][N:15]([CH2:18][CH3:19])[CH2:16][CH3:17])[C:2]1=2.[C:20]([OH:25])(=[O:24])[C:21]([OH:23])=[O:22]>C(OCC)(=O)C>[C:20]([OH:25])(=[O:24])[C:21]([OH:23])=[O:22].[S:1]1[CH:5]=[CH:4][C:3]2[CH:6]=[CH:7][CH:8]=[C:9]([CH2:10][CH2:11][O:12][CH2:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19])[C:2]1=2

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 22666326HCID 22666326, compound

Product 1

HCID 22666325HCID 22666325, compoundYield 78.2%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

In 10 mL of ethyl acetate is dissolved 1.10 g of N-[2-(2-benzo[b]thiophen-7-ylethoxy)ethyl]-N,N-diethylamine, to which is added 10 mL of a solution of 0.39 g of oxalic acid in ethyl acetate. The resulting mixture is stirred at ambient temperature for 2 hours. The deposited crystal is collected by filtration, washed with ethyl acetate, and dried to obtain 1.14 g of N-[2-(2-benzo[b]thiophen-7-ylethoxy)ethyl]-N,N-diethylamine oxalate.

Workup

  1. filtrationThe deposited crystal is collected by filtration
  2. washwashed with ethyl acetate
  3. customdried

Sources & evidence

ORD record
ord-d8d974f0b69c4009b6875ccc33875abe
Source dataset
uspto-grants-2004_09
Patent number
US06797726B1

Reaction notes

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