HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-methylsulfonyl-D-phenylalanyl-proline → 1-(2-(R)-Methanesulfonylamino-3-phenyl-propionyl)-pyrrolidin-2-(S)-carboxylic acid (1-amino-isoquinolin-6-ylmethyl)-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-methylsulfonyl-D-phenylalanyl-proline | HCID 10893176 | — |
| Edukt | 1-(2-(R)-Acetylamino-3-biphenyl-4yl-propionyl)-pyrrolidin-2-(S)-carboxylic acid (1-amino-isoquinolin-6-ylmethyl)-amide | HCID 86588694 | — |
| Produkt | 1-(2-(R)-Methanesulfonylamino-3-phenyl-propionyl)-pyrrolidin-2-(S)-carboxylic acid (1-amino-isoquinolin-6-ylmethyl)-amide | HCID 54108879 | 90% |
Reaktionsschritte
Using the procedure described in example 97f 0.140 g of 1-(2-(R)-methanesulfonylamino-3-phenyl-propionyl)-pyrrolidin-2-(S)-carboxylic acid was converted into 0.180 g (90%) of the title compound. (+)-APCI-MS: 496 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06797710B2 |
| Quelldatensatz | uspto-grants-2004_09 |
| ORD ID | ord-4ed2b316a890427389b58b852098c564 |
| Quellennotiz | uspto-grants-2004_09 |