Methanol → HCID 23074222, compound

HRID 1008755Notes

Reaction equation

HRID 1008755 reaction equation
S(Cl)([Cl:3])=O.[NH2:5][CH:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[C:7]([OH:9])=[O:8].[CH3:15]O>>[ClH:3].[NH2:5][CH:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[C:7]([O:9][CH3:15])=[O:8]

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 227939(+-)-2-Aminoheptanoic acid

Product 1

HCID 23074222HCID 23074222, compound

Conditions

Temperature
60 °C

Procedure

Thionyl chloride (2.19 g) (supplied from Wako Pure Chemical Industries) was added dropwise to a suspension of 2.18 g of 2-aminoheptanoic acid in 50 mL of methanol, and stirred at 60° C. overnight. Methanol and thionyl chloride were distilled off, and the residue was washed with 20 mL of ether, to yield 2.84 g of the title compound.

Workup

  1. distillationMethanol and thionyl chloride were distilled off
  2. washthe residue was washed with 20 mL of ether

Sources & evidence

ORD record
ord-cbed6ce868b44b4cb3424282e166a3e6
Source dataset
uspto-grants-2011_07
Patent number
US07973030B2

Reaction notes

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