tert-butyl N-(4-ethyl-5-methylsulfanyl-thiazol-2-yl)carbamate → HCID 86630962, compound

Participants

Reaction Conditions

Reaction Steps

The above prepared (4-ethyl-5-methylsulfanyl-thiazol-2-yl)-carbamic acid tert-butyl ester (1.067 g, 3.888 mmol) was treated with 20 mL of HCl (4 M in dioxane). After 48 h at RT the reaction mixture was evaporated to dryness and, since still some starting material was present, the procedure repeated, but this time the temperature was raised to 30° C. Careful evaporation and drying left 0.814 g of the title compound as hydrochloride.

Provenance & Evidence