反应详情

温度

30 °C

The above prepared (4-ethyl-5-methylsulfanyl-thiazol-2-yl)-carbamic acid tert-butyl ester (1.067 g, 3.888 mmol) was treated with 20 mL of HCl (4 M in dioxane). After 48 h at RT the reaction mixture was evaporated to dryness and, since still some starting material was present, the procedure repeated, but this time the temperature was raised to 30° C. Careful evaporation and drying left 0.814 g of the title compound as hydrochloride.

1. customAfter 48 h at RT the reaction mixture was evaporated to dryness
2. customCareful evaporation
3. customdrying
4. waitleft 0.814 g of the title compound as hydrochloride