HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Trifluoromethoxyphenoxy)-acetic acid tert-butyl ester → 2-(4-(Trifluoromethoxy)phenoxy)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Trifluoromethoxyphenoxy)-acetic acid tert-butyl ester | HCID 57787045 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 2-(4-(Trifluoromethoxy)phenoxy)acetic acid | HCID 697705 | — |
Reaction Steps
TFA (80 mL) was added to (4-trifluoromethoxyphenoxy)-acetic acid tert-butyl ester (25.8 g, 88 mmol). The mixture was stirred for three hours. The TFA was removed in vacuo affording the title compound as a white solid: MS (ESI-LCMS) for C9H6F3O4: 235 (M-H—).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07973061B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-791cd66cc89b4d09bf136f5323ef1ba6 |
| Source note | uspto-grants-2011_07 |