HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Chloro-2-(3,4,5-trifluorophenyl)pentanoic acid hydrazide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-butyl N'-[5-chloro-2-(3,4,5-trifluorophenyl)pentanoyl]hydrazinecarboxylate | HCID 66839143 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 5-Chloro-2-(3,4,5-trifluorophenyl)pentanoic acid hydrazide hydrochloride | HCID 66839231 | 200.1% |
Reaction Steps
A solution of 4 N hydrochloric acid in acetic acid (2 mL) was added to a solution of tert-butyl N′-[5-chloro-2-(3,4,5-trifluorophenyl)pentanoyl]hydrazinecarboxylate (300 mg) in ethyl acetate (2 mL), and the reaction solution was stirred at room temperature for one hour. The reaction solution was concentrated under reduced pressure to obtain 250 mg of the title compound. The property value of the compound is as follows.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07973033B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-dfecf210fb2c405c887613a844f77461 |
| Source note | uspto-grants-2011_07 |