Calcium Chloride → HCID 86633380, compound

HRID 1009679Notes

Reaction equation

HRID 1009679 reaction equation
[Na].[S:2]([CH2:6][C@H:7]1[O:12][C@H:11]([O:13][CH2:14][CH2:15][CH2:16][O:17][C:18](=[O:36])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[C@H:10]([OH:37])[C@@H:9]([OH:38])[C@@H:8]1[OH:39])([OH:5])(=[O:4])=[O:3].[Cl-].[Ca+2:41].[Cl-]>O>[Ca:41].[S:2]([CH2:6][C@H:7]1[O:12][C@H:11]([O:13][CH2:14][CH2:15][CH2:16][O:17][C:18](=[O:36])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[C@H:10]([OH:37])[C@@H:9]([OH:38])[C@@H:8]1[OH:39])([OH:5])(=[O:3])=[O:4]

Participants

4

Reactant 2

HCID 5284359Calcium ChlorideHCID 86633377HCID 86633377, compound

Product 1

HCID 86633380HCID 86633380, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2.15 g of 3-O-(6-sulfo-α-D-quinovopyranosyl)-1-O-stearoyl-propane-1,3-diol sodium salt was dissolved in 60 ml of water, adsorbed to a WAKOGEL® 100C18 (manufactured by Wako Pure Chemical Industries, Ltd.) column, and 500 ml of 1% calcium chloride solution was poured into the column for substitution, and washed with 500 ml of distilled water. Thereafter, elution was performed with 200 ml each of 50%, 80%, and 100% methanol, and reprecipitated from 98% heated ethanol to obtain 1.47 g of 3-O-(6-sulfo-α-D-quinovopyranosyl)-1-O-stearoyl-propane-1,3-diol calcium salt.

Workup

  1. additionwas poured into the column for substitution
  2. washwashed with 500 ml of distilled water
  3. washThereafter, elution
  4. customreprecipitated from 98%
  5. temperatureheated ethanol

Sources & evidence

ORD record
ord-36467d09ef724d2e848ce5cd4a38f539
Source dataset
uspto-grants-2011_07
Patent number
US07973145B2

Reaction notes

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