2-Methoxynaphthalene → Salicylic Acid

HRID 1009843Notes

Reaction equation

HRID 1009843 reaction equation
COC1C=CC2C(=CC=CC=2)C=1.[C:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[O:22]C)([OH:15])=[O:14]>>[OH:22][C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=1[C:13]([OH:15])=[O:14]

Participants

3

Reactant 2

HCID 71192-MethoxynaphthaleneHCID 113702-Methoxybenzoic acid

Product 1

HCID 338Salicylic AcidYield 89.9%

Procedure

The method described in Example 4 is applied with the alteration that instead of 2-methoxynaphthalene 3.04 g (20 mmol) of 1-carboxy-2-methoxybenzene is used yielding 2.48 g (89.9%) of 2-hydroxybenzoic acid.

Sources & evidence

ORD record
ord-fdfc74c0e5fb4b09892c4f48bc5e34b5
Source dataset
uspto-grants-2011_07
Patent number
US07973185B2

Reaction notes

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