2-Methoxynaphthalene → 4-Hydroxybenzoic Acid

HRID 1009844Notes

Reaction equation

HRID 1009844 reaction equation
COC1C=CC2C(=CC=CC=2)C=1.[C:13]([C:16]1[CH:21]=[CH:20][C:19]([O:22]CC)=[CH:18][CH:17]=1)([OH:15])=[O:14]>>[OH:22][C:19]1[CH:20]=[CH:21][C:16]([C:13]([OH:15])=[O:14])=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 71192-MethoxynaphthaleneHCID 120934-Ethoxybenzoic acid

Product 1

HCID 1354-Hydroxybenzoic AcidYield 61.2%

Procedure

The method described in Example 4 is applied with the alteration that instead of 2-methoxynaphthalene 3.32 g (20 mmol) of 1-carboxy-4-ethoxybenzene is used yielding 1.86 g (61.2%) of 4-hydroxybenzoic acid.

Sources & evidence

ORD record
ord-cd2745468ea443ff9adf6748cb5b89d9
Source dataset
uspto-grants-2011_07
Patent number
US07973185B2

Reaction notes

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