Hydrochloric Acid → HCID 22605443, compound

HRID 1009911Notes

Reaction equation

HRID 1009911 reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][N:5]([C:7]2[CH:16]=[CH:15][C:10]([C:11]([O:13]C)=[O:12])=[CH:9][CH:8]=2)[CH:6]=1.[OH-].[Na+].Cl>CO>[CH3:1][C:2]1[N:3]=[CH:4][N:5]([C:7]2[CH:16]=[CH:15][C:10]([C:11]([OH:13])=[O:12])=[CH:9][CH:8]=2)[CH:6]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 46942000HCID 46942000, compound

Product 1

HCID 22605443HCID 22605443, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution (5 ml) of methyl 4-(4-methyl-1H-imidazol-1-yl)benzoate (137 mg, 0.635 mmol) in methanol was added 1M sodium hydroxide (5 ml), and the mixture was stirred at room temperature for 3 hrs. 1M Hydrochloric acid (5 ml) was added to the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was used for the next reaction without purification.

Workup

  1. customthe solvent was evaporated under reduced pressure
  2. customThe residue was used for the next reaction without purification

Sources & evidence

ORD record
ord-9944bbd18ab2432aaef4b4715d146693
Source dataset
uspto-grants-2011_07
Patent number
US07973163B2

Reaction notes

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