Hydrochloric Acid → HCID 54402950, compound

HRID 1010522Notes

Reaction equation

HRID 1010522 reaction equation
C([O:3][C:4](=[O:13])[CH2:5][N:6]1[CH:10]=[C:9]([CH2:11][CH3:12])[N:8]=[CH:7]1)C.Cl>>[CH2:11]([C:9]1[N:8]=[CH:7][N:6]([CH2:5][C:4]([OH:13])=[O:3])[CH:10]=1)[CH3:12]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 57731307HCID 57731307, compound

Product 1

HCID 54402950HCID 54402950, compound

Procedure

1.7 g (9.5 mmol) of (4-ethyl-imidazol-1-yl)-acetic acid ethyl ester are dissolved in 47 ml (190 mmol) 4N HCl and the mixture is heated to reflux. After 2 h the mixture is cooled to rt and the solvent is removed in vacuo. The resulting product is used without further purification.

Workup

  1. temperaturethe mixture is heated to reflux
  2. customthe solvent is removed in vacuo
  3. customThe resulting product is used without further purification

Sources & evidence

ORD record
ord-bb57c63f9b0d41b99bff4471bff17847
Source dataset
uspto-grants-2011_07
Patent number
US07977323B2

Reaction notes

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