HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2{[(6-Chloro(3-pyridyl))methyl]propylamino}ethan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | 2-[(6-Chloro-pyridin-3-ylmethyl)-amino]-ethanol | HCID 15390297 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 2{[(6-Chloro(3-pyridyl))methyl]propylamino}ethan-1-ol | HCID 61424932 | — |
Reaction Steps
This compound was made in a manner analogous to that set forth in Step B of Example 2, using 11.3 grams (about 0.055 mole) of 2-{[(6-chloro-3-pyridyl)methyl]amino}ethan-1-ol, 25.4 grams (0.150 mole) of 1-iodopropane, and 14.5 grams (0.143 mole) of triethylamine in 50 mL of acetonitrile. The yield of the subject compound was about 2.2 grams.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977332B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-c8075ee458f84ecdb767596ff2d08256 |
| Source note | uspto-grants-2011_07 |