HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl chloroformate → HCID 67315607, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl chloroformate | HCID 10387 | — |
| Reactant | ethyl (2R)-5-oxopyrrolidine-2-carboxylate | HCID 643508 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67315607 | HCID 67315607 | — |
Reaction Steps
9.1 Reaction of 1.0 g of ethyl(R)-5-oxopyrrolidine-2-carboxylate, 949.8 μl of benzyl chloroformate, 6.9 ml of bis(trimethylsilyl)lithium amide (in THF) in 25 ml of THF under standard conditions and work-up gives 730 mg of ethyl(R)-5-oxo-N-benzyloxycarbonylpyrrolidine-2-carboxylate (“17”).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977343B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-a65930fc04e24caa890b77a73a1bab32 |
| Source note | uspto-grants-2011_07 |