反应详情

9.1 Reaction of 1.0 g of ethyl(R)-5-oxopyrrolidine-2-carboxylate, 949.8 μl of benzyl chloroformate, 6.9 ml of bis(trimethylsilyl)lithium amide (in THF) in 25 ml of THF under standard conditions and work-up gives 730 mg of ethyl(R)-5-oxo-N-benzyloxycarbonylpyrrolidine-2-carboxylate (“17”).