HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminophenylacetic acid → HCID 67021355, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminophenylacetic acid | HCID 14533 | — |
| Reactant | 4-Chloro-3-nitropyridine | HCID 2735781 | — |
| Reactant | Dioxane Methanol | HCID 21966525 | — |
| Product | HCID 67021355 | HCID 67021355 | — |
Reaction Steps
A mixture of 0.500 g of 4-chloro-3-nitro-pyridine (LANCASTER) and 0.467 g of (4-amino-phenyl)-acetic acid (Aldrich) in 10 ml of MeOH/dioxane (1/1 v/v) is stirred and refluxed for 6 hours. The mixture obtained is allowed to cool to rt and is concentrated in vacuo. Crude [4-(3-nitro-pyridin-4-ylamino)-phenyl]-acetic acid methyl ester is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977338B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-2e8109990e08481c8bc7c5a690bb8b6d |
| Source note | uspto-grants-2011_07 |