Ethyl acetate hexane → HCID 67021312, compound

HRID 1010724Notes

Reaction equation

HRID 1010724 reaction equation
[CH2:1]([O:3][C:4](=[O:21])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13]2[C:18]([NH2:19])=[CH:17][CH:16]=[CH:15][N:14]=2)=[CH:8][C:7]=1[Cl:20])[CH3:2].[CH3:22]CCCCC.CCOC(C)=O>>[CH2:1]([O:3][C:4](=[O:21])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([N:12]2[C:13]3=[N:14][CH:15]=[CH:16][CH:17]=[C:18]3[N:19]=[CH:22]2)=[CH:8][C:7]=1[Cl:20])[CH3:2]

Participants

3

Reactant 2

HCID 21226206Ethyl acetate hexaneHCID 67021554[4-(3-Amino-pyridin-2-ylamino)-2-chloro-phenyl]-acetic acid ethyl ester

Product 1

HCID 67021312HCID 67021312, compound

Procedure

is obtained analogously to the method as described in Step 1.2 but using [4-(3-amino-pyridin-2-ylamino)-2-chloro-phenyl]-acetic acid ethyl ester instead of [4-(3-amino-pyridin-2-ylamino)-phenyl]-acetic acid methyl ester as a starting material. ES-MS: 316.1 [M+H]+; single peak at tR=4.24 min (System 1); Rf=0.16 (Hexane/EtOAc, 1:1).

Workup

  1. customis obtained analogously to the method

Sources & evidence

ORD record
ord-b7a335c219ca49a79174d277c441552f
Source dataset
uspto-grants-2011_07
Patent number
US07977338B2

Reaction notes

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