HuagongsheHuagongshe Chemistry Print Report · For research reference only
10-(Phenylmethyl)-5,8-dioxa-10-azadispiro[2.0.4.3]undecane → 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 10-(Phenylmethyl)-5,8-dioxa-10-azadispiro[2.0.4.3]undecane | HCID 9942895 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane | HCID 22417222 | — |
Reaction Steps
10-benzyl-5,8-Dioxa-10-azadispiro[2.0.4.3]undecane (A) (1.0 g, similar prepared according to JMC 37, 3344) was mixed with Pd—C (10%, 600 mg) in EtOH (40 ml) and hydrogenated under H2 at 50 psi for 5 hour. The reaction was filtered through Celite and evaporated to give 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane (B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977346B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-2fc18880c14545e0bf97678e81301cd0 |
| Source note | uspto-grants-2011_07 |