HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromoethanol → 10-(2-hydroxyethyl)-5,8-Dioxa-10-azadispiro[2.0.4.3]undecane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromoethanol | HCID 10898 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane | HCID 22417222 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 10-(2-hydroxyethyl)-5,8-Dioxa-10-azadispiro[2.0.4.3]undecane | HCID 16738498 | — |
Reaction Steps
The compound (B) (100 mg) was mixed with 2-Bromoethanol (100 mg) and K2CO3 (120 mg) in Acetonitrile. The reaction was refluxed overnight and filtered, the filtrate was evaporated and purified on silica gel column to give the titled product. Mass: (M+1), 200
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977346B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-68da0bef6e6647ec8ad3506260f2ab14 |
| Source note | uspto-grants-2011_07 |