HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 10-(3-hydroxypropyl)-5,8-Dioxa-10-azadispiro[2.0.4.3]undecane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Bromo-1-propanol | HCID 12308 | — |
| Reactant | 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane | HCID 22417222 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 10-(3-hydroxypropyl)-5,8-Dioxa-10-azadispiro[2.0.4.3]undecane | HCID 16738282 | — |
Reaction Steps
The compound (B) (100 mg) was mixed with 3-Bromopropanol (120 mg) and K2CO3 (120 mg) in Acetonitrile. The reaction was refluxed overnight and filtered; the filtrate was evaporated and purified on silica gel column to give the titled product. Mass: (M+1), 214
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977346B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-2a1f931bc48f4510bf36435f4fabf701 |
| Source note | uspto-grants-2011_07 |