HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 5-(2-Hydroxyethyl)-5-azaspiro[2.4]heptan-7-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 5-(2-Hydroxyethyl)-5-azaspiro[2.4]heptan-7-one | HCID 16738283 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-(2-Hydroxyethyl)-5-azaspiro[2.4]heptan-7-ol | HCID 16738285 | — |
Reaction Steps
5-(2-Hydroxyethyl)-5-azaspiro[2.4]heptan-7-one (100 mg) was dissolved into Methanol (8 ml) and stirred at RT. NaBH4 (100 mg) was added to the reaction and stirred at RT for 30 minutes. The reaction was evaporated and purified by column chromatography to give title compound. Mass: (M+1), 158
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977346B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-0effb4b5009a43d2a870d2f4eaaaca35 |
| Source note | uspto-grants-2011_07 |