Trifluoroacetic acid → HCID 178446274, compound

Participants

Reaction Steps

To a solution of 8-methoxy-N2-pentyl-9-(tetrahydro-2H-pyran-2-yl)-9H-purine-2,6-diamine (520 mg) in dry MeOH (5.2 mL) was added TFA (0.52 mL) and the mixture was stirred at room temperature for 48 h. The reaction was concentrated in vacuo to give an orange residue which was triturated with Et2O and filtered to give the title compound as an off-white solid (223 mg).

Provenance & Evidence