Bromide ion → 3-(3-Fluoro-4-methoxy-benzoyl)-1-(6-methyl-pyridin-2-ylmethyl)-1H-quinolin-4-one

HRID 101099Notes

Reaction equation

HRID 101099 reaction equation
[Br-:26].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:1][O:2][N:3]([C:4](=[O:5])[c:6]1[cH:7][n:8]([CH2:17][c:18]2[n:19][c:20]([CH3:24])[cH:21][cH:22][cH:23]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2[c:15]1=[O:16])[CH3:25].[F:27][c:28]1[cH:29][c:30]([Mg+:36])[cH:31][cH:32][c:33]1[O:34][CH3:35]>>[C:4](=[O:5])([c:6]1[cH:7][n:8]([CH2:17][c:18]2[n:19][c:20]([CH3:24])[cH:21][cH:22][cH:23]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2[c:15]1=[O:16])[c:30]1[cH:29][c:28]([F:27])[c:33]([O:34][CH3:35])[cH:32][cH:31]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 577545121-(6-Methyl-pyridin-2-ylmethyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid methoxy-methyl amideHCID 178491922HCID 178491922, compound

Product 1

HCID 577546633-(3-Fluoro-4-methoxy-benzoyl)-1-(6-methyl-pyridin-2-ylmethyl)-1H-quinolin-4-one

Sources & evidence

ORD record
ord-ab6ccce8314543728a0b6e9f4ad965cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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