Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → HCID 178495541, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 2-{[1-methyl-2-(methoxy)ethyl]oxy}-8-(methoxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine | HCID 57699748 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 178495541 | HCID 178495541 | — |
반응 단계
TFA (7.5 ml) was added to a solution of 2-{[1-methyl-2-(methoxy)ethyl]oxy}-8-(methoxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine (4.7 g, 13.9 mmol) in MeOH (30 ml) with stirring. The mixture was left to stand at room temperature for 1 day. A white solid formed which was filtered off and washed with ethyl acetate. This gave product (3.7 g, 76.1%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07977344B2 |
| 출처 데이터셋 | uspto-grants-2011_07 |
| ORD ID | ord-84b347f393bc44c7b96f208e84d7e23f |
| 출처 메모 | uspto-grants-2011_07 |