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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011078Generated: November 1, 2026

(3R)-3-(2-bromoethyl)oxolane → N2-Butyl-8-(methyloxy)-9-[2-[(3S)-tetrahydro-3-furanyl]ethyl}-9H-Purine-2,6-diamine

https://huagongshe.com/reaction/1011078

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3R)-3-(2-bromoethyl)oxolaneHCID 52324315—
ReactantHCID 178448877HCID 178448877—
ProductN2-Butyl-8-(methyloxy)-9-[2-[(3S)-tetrahydro-3-furanyl]ethyl}-9H-Purine-2,6-diamineHCID 57699685—

Reaction Steps

Prepared similarly to Intermediate 215 from N2-butyl-8-(methyloxy)-3H-purine-2,6-diamine trifluoroacetate and (3R)-3-(2-Bromoethyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-6ca57d8b32fe456ba7c779b31c3496a6
Source noteuspto-grants-2011_07