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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011091Generated: October 31, 2026

(3R)-3-(2-bromoethyl)oxolane → 2-(Butyloxy)-8-(methyloxy)-9-[2-[(3S)-tetrahydro-3-furanyl]ethyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011091

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3R)-3-(2-bromoethyl)oxolaneHCID 52324315—
ReactantHCID 178450357HCID 178450357—
Product2-(Butyloxy)-8-(methyloxy)-9-[2-[(3S)-tetrahydro-3-furanyl]ethyl]-9H-purin-6-amineHCID 57699830—

Reaction Steps

Prepared similarly to Intermediate 215 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and (3R)-3-(2-bromoethyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-dd5e72571b79429abe88bbbd7623b017
Source noteuspto-grants-2011_07