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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011131Generated: October 27, 2026

2-(2-Bromoethyl)oxolane → 2-{[(1R)-1-methylbutyl]oxy}-8-(methyloxy)-9-[2-(tetrahydro-2-furanyl)ethyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011131

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Bromoethyl)oxolaneHCID 53691871—
ReactantHCID 178448284HCID 178448284—
Product2-{[(1R)-1-methylbutyl]oxy}-8-(methyloxy)-9-[2-(tetrahydro-2-furanyl)ethyl]-9H-purin-6-amineHCID 57699733—

Reaction Steps

Prepared similarly to Intermediate 290 from 2-{[(1R)-1-methylbutyl]oxy}-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 2-(2-bromoethyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-60ca91350443462298e53cbd7b30cb13
Source noteuspto-grants-2011_07