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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011143Generated: November 1, 2026

4-(3-Bromopropyl)oxane → 2-{[(1R)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[3-(tetrahydro-2H-pyran-4-yl)propyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011143

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Bromopropyl)oxaneHCID 57699704—
ReactantHCID 178448284HCID 178448284—
Product2-{[(1R)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[3-(tetrahydro-2H-pyran-4-yl)propyl]-9H-purin-6-amineHCID 57699694—

Reaction Steps

Prepared similarly to Intermediate 216 from 2-{[(1R)-1-methylbutyl]oxy}-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 4-(3-bromopropyl)tetrahydro-2H-pyran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-8a87fe4f999342ff867074f017b9c7dd
Source noteuspto-grants-2011_07