反应详情

A solution of 2-butyloxy-8-methoxy-9-[2-(tetrahydro-2H-pyran-2-yl)ethyl]-9H-purin-6-amine (88 mg) in methanol (2 mL) was treated with 4N HCl in 1,4-dioxane (1 mL) for 1 h. The reaction was evaporated and the residue treated with water then basified with saturated sodium bicarbonate solution. The resulting white solid was filtered, washed with water and dried to give the title compound (78.1 mg).

1. customThe reaction was evaporated
2. additionthe residue treated with water
3. filtrationThe resulting white solid was filtered
4. washwashed with water
5. customdried