反应详情

A solution of 2-butyloxy-9-[(2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl]-8-methoxy-9H-purin-6-amine (161 mg) in methanol (1 mL) was treated with 4N HCl in 1,4-dioxane (0.5 mL) for 1 h. The reaction was evaporated and the residue treated with water then basified with saturated sodium bicarbonate solution. The resulting solid was filtered, washed with water and dried to give the title compound (122 mg).

1. customThe reaction was evaporated
2. additionthe residue treated with water
3. filtrationThe resulting solid was filtered
4. washwashed with water
5. customdried