HRID1011253

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[C@@H]1CN(c2ccc([N+](=O)[O-])cc2F)[C@@H](C)CN1C

HCID57664351

未命名化合物

结构：C[C@@H]1CN(c2ccc([N+](=O)[O-])cc2)[C@@H](C)CN1

HCID57664370

rel-(2R,5S)-2,5-Dimethyl-1-(4-nitrophenyl)piperazine

C12H17N3O2

PRODUCTS

生成物

结构：C[C@@H]1CN(C)[C@@H](C)CN1c1ccc([N+](=O)[O-])cc1

HCID131729017

未命名化合物

收率 111%

PROCEDURE

实验过程

Crude racemic-trans-[1,2,5-trimethyl-4-(4-nitrophenyl)piperazine] (7.48 g, 111% recovery) is prepared according to the method described above for the synthesis of racemic-1-(2-fluoro-4-nitrophenyl)-trans-2,4,5-trimethylpiperazine from racemic-[trans-2,5-dimethyl-1-(4-nitrophenyl)-piperazine] (6.34 g, 25.0 mmol). LCMS-ESI (m/z): calcd for C13H19N3O2, 249; [M+H]+ found, 250.