HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 67315548, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 76798884 | HCID 76798884 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 67315548 | HCID 67315548 | 54.1% |
Reaction Steps
A solution of morpholine (200 mg, 2.29 mmol) in 4 mL of isopropanol is treated with 3-(6-Chloro-1-ethyl-1H-furo[3,4-c]pyridin-3-ylidene)-1,3-dihydro-indol-2-one (100 mg, 0.31 mmol) in one portion and the reaction mixture is heated to reflux for 72 h. The reaction mixture is cooled to room temperature and the solid which precipitated from solution is collected by filtration and dried to give the title compound as a yellow solid (61 mg, 54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977351B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-b7bbc1256263446daffa3e781b4068db |
| Source note | uspto-grants-2011_07 |