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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011394Generated: October 31, 2026

Morpholine → HCID 67315548, compound

https://huagongshe.com/reaction/1011394

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantHCID 76798884HCID 76798884—
SolventIsopropanolHCID 3776—
ProductHCID 67315548HCID 6731554854.1%

Reaction Steps

A solution of morpholine (200 mg, 2.29 mmol) in 4 mL of isopropanol is treated with 3-(6-Chloro-1-ethyl-1H-furo[3,4-c]pyridin-3-ylidene)-1,3-dihydro-indol-2-one (100 mg, 0.31 mmol) in one portion and the reaction mixture is heated to reflux for 72 h. The reaction mixture is cooled to room temperature and the solid which precipitated from solution is collected by filtration and dried to give the title compound as a yellow solid (61 mg, 54%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977351B2
Source datasetuspto-grants-2011_07
ORD IDord-b7bbc1256263446daffa3e781b4068db
Source noteuspto-grants-2011_07