Hydrochloric Acid → 5-(4-Chloro-phenyl)-6-cyclobutoxy-pyridin-3-ylamine

HRID 101157Notes

Reaction equation

HRID 101157 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[cH:9][n:10][c:11]([O:21][CH:22]2[CH2:23][CH2:24][CH2:25]2)[c:12](-[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:13]1)([CH3:5])([CH3:6])[CH3:26].[ClH:33].[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1>>[NH2:7][c:8]1[cH:9][n:10][c:11]([O:21][CH:22]2[CH2:23][CH2:24][CH2:25]2)[c:12](-[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 68071757[5-(4-Chloro-phenyl)-6-cyclobutoxy-pyridin-3-yl]-carbamic acid tert-butyl ester

Product 1

HCID 672811445-(4-Chloro-phenyl)-6-cyclobutoxy-pyridin-3-ylamine

Sources & evidence

ORD record
ord-acf0cfeaa98c4c89b67cabeb02ad9b7f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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