Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011578Generated: November 1, 2026

Pyrrolidine → HCID 25002216, compound

https://huagongshe.com/reaction/1011578

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantHCID 59285987HCID 59285987—
ProductHCID 25002216HCID 2500221642%

Reaction Conditions

Temperature120 °C

Reaction Steps

Pyrrolidine (0.5 mL) was added to 2-aminocarbonylamino-5-[2-(3-chloropropyloxy)phenyl]pyrrole-3-carboxamide (Compound No. 4-29, 30 mg, 0.090 mmol), the whole was sealed and stirred at 120° C. for 5 hours. This mixture was purified by silica gel column chromatography to give the target compound (14 mg) as a brown amorphous Powder (Yield 42%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977371B2
Source datasetuspto-grants-2011_07
ORD IDord-d26a0cb45c5d4237aeebcf4a586b5078
Source noteuspto-grants-2011_07