Hydrochloric Acid → HCID 178519992, compound

Participants

Reaction Steps

(4R)-tert-butyl 6-((tert-butyldimethylsilyloxy)methyl)-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate (35) (1.38 g, 3.51 mmol) was covered with HCl in dioxane (4 N, 5 mL).). The reaction mixture was stirred at rt for 1 hr after which it was concentrated under vacuum to give ((4R)-4-cyclopropyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-6-yl)methanol (36). Retention time (min)=0.203, method [1], MS (m/z) 180.2 (M+H)+.

Provenance & Evidence