Chloroform → Methyl 6-amino-4-bromopyridine-2-carboxylate

HRID 101168Notes

Reaction equation

HRID 101168 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:16](=[O:17])[O:18][CH3:19])[n:5][c:6]([NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[cH:7]1.[CH:27]([Cl:28])([Cl:29])[Cl:30].[OH:20][C:21]([C:22]([F:23])([F:24])[F:25])=[O:26]>>[Br:1][c:2]1[cH:3][c:4]([C:16](=[O:17])[O:18][CH3:19])[n:5][c:6]([NH2:8])[cH:7]1

Participants

4

Reactant 3

HCID 6212ChloroformHCID 6422Trifluoroacetic acidHCID 25067269Methyl 4-bromo-6-[(tert-butoxycarbonyl)amino]pyridine-2-carboxylate

Product 1

HCID 29919299Methyl 6-amino-4-bromopyridine-2-carboxylate

Sources & evidence

ORD record
ord-e6ab124d9580470eb6cad3abe0ee1c48
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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