huagongshe.com
HRID1011870

反应详情

EQUATION

反应方程式

HRID 1011870 的结构方程式

REACTANTS

反应物

3
结构：O=P([O-])([O-])[O-].[K+].[K+].[K+]
HCID62657

Tripotassium phosphate

K3O4P

结构：OB(O)/C=C/c1ccc(Cl)cc1
HCID642694

未命名化合物

结构：Cc1nn(-c2cccc(Br)c2)c(C)c1C(=O)O
HCID2763997

1-(3-Bromophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid

C12H11BrN2O2

PRODUCTS

生成物

1
结构：Cc1nn(-c2cccc(/C=C/c3ccc(Cl)cc3)c2)c(C)c1C(=O)O
HCID67315510

未命名化合物

收率 63%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

In analogy to the procedure described in Example 14C], but with 2.8 eq of K3PO4, 1-(3-bromo-phenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid and trans-2-(4-chlorophenyl)vinylboronic acid gave after suspending in CH2Cl2 and filtration the title compound in 63% yield as light yellow solid. MS: 352.2 (M+, 1 Cl).

WORKUP

后处理

  1. customgave
  2. filtrationfiltration the title compound in 63% yield as light yellow solid