Hydrochloric Acid → HCID 67315010, compound

HRID 1011884Notes

Reaction equation

HRID 1011884 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C@@H:11]([OH:14])[C@H:10]([N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)[CH2:9]1)=O)(C)(C)C.[ClH:20]>>[ClH:20].[N:15]1([C@H:10]2[C@H:11]([OH:14])[CH2:12][CH2:13][NH:8][CH2:9]2)[CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 67315423HCID 67315423, compound

Product 1

HCID 67315010HCID 67315010, compound

Procedure

The titled product was prepared by deprotection of (trans)-4-hydroxy-3-pyrrolidin-1-yl-piperidine-1-carboxylic acid tert-butyl ester (described in Heterocycles 1994, 39, 1, 163) with hydrochloric acid analogously to intermediate 30. MS: 171.0 (MH+).

Sources & evidence

ORD record
ord-5811a237d1da4e39ad1d6f93bdbc54de
Source dataset
uspto-grants-2011_07
Patent number
US07977358B2

Reaction notes

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