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4-(1-Pyrrolidinyl)piperidine → (1-{3-[(E)-2-(4-Chloro-phenyl)-vinyl]-phenyl}-3,5-diethyl-1H-pyrazol-4-yl)-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(1-Pyrrolidinyl)piperidine | HCID 78703 | — |
| 反応物 | 1-{3-[(E)-2-(4-Chloro-phenyl)-vinyl]-phenyl}-3,5-diethyl-1H-pyrazole-4-carboxylic acid | HCID 67313975 | — |
| 生成物 | (1-{3-[(E)-2-(4-Chloro-phenyl)-vinyl]-phenyl}-3,5-diethyl-1H-pyrazol-4-yl)-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone | HCID 57555029 | — |
反応手順
In analogy to the procedure described for example 2, 1-{3-[(E)-2-(4-chloro-phenyl)-vinyl]-phenyl}-3,5-diethyl-1H-pyrazole-4-carboxylic acid (intermediate 1) and 4-pyrrolidin-1-yl-piperidine gave the title compound as colorless oil. MS: 517.3 (MH+, 1 Cl).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07977358B2 |
| 出典データセット | uspto-grants-2011_07 |
| ORD ID | ord-d09422bf4d6d4e2eae15fe202fb10fc5 |
| 出典メモ | uspto-grants-2011_07 |