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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011890Generated: November 4, 2026

HCID 67315889, compound → HCID 57555051, compound

https://huagongshe.com/reaction/1011890

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67315889HCID 67315889—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 57555051HCID 57555051—

Reaction Steps

0.027 g of Pd—C (10%) was added to a solution of 0.11 g (0.30 mmol) of [3,5-diethyl-1-(3-hex-1-ynyl-phenyl)-1H-pyrazol-4-yl]-[4-(2-hydroxy-ethyl)-[1,4]diazepan-1-yl]-methanone in 5 ml of MeOH and the reaction mixture was then hydrogenated with H2 (1 bar) at RT for 1 hour. After removal the catalyst by filtration, the solvent was evaporated completely to afford the title compound as light yellow oil. MS: 455.3 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977358B2
Source datasetuspto-grants-2011_07
ORD IDord-20c31ad3dfc5453da2540b68d21e25a7
Source noteuspto-grants-2011_07