HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67315889, compound → HCID 57555051, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67315889 | HCID 67315889 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 57555051 | HCID 57555051 | — |
Reaction Steps
0.027 g of Pd—C (10%) was added to a solution of 0.11 g (0.30 mmol) of [3,5-diethyl-1-(3-hex-1-ynyl-phenyl)-1H-pyrazol-4-yl]-[4-(2-hydroxy-ethyl)-[1,4]diazepan-1-yl]-methanone in 5 ml of MeOH and the reaction mixture was then hydrogenated with H2 (1 bar) at RT for 1 hour. After removal the catalyst by filtration, the solvent was evaporated completely to afford the title compound as light yellow oil. MS: 455.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977358B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-20c31ad3dfc5453da2540b68d21e25a7 |
| Source note | uspto-grants-2011_07 |