HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-iodobenzene → HCID 178463853, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-iodobenzene | HCID 12510 | — |
| Reactant | (3-Diethylamino-pyrrolidin-1-yl)-[5-(3-ethynyl-phenyl)-4-methyl-1H-pyrazol-3-yl]-methanone | HCID 178436202 | — |
| Product | HCID 178463853 | HCID 178463853 | 74% |
Reaction Steps
In analogy to the procedure described in Example 31F], 1-chloro-4-iodobenzene and (3-diethylamino-pyrrolidin-1-yl)-[5-(3-ethynyl-phenyl)-4-methyl-1H-pyrazol-3-yl]-methanone (Example 31E]) gave the title compound in 74% yield light yellow powder. MS: 461.1 (MH+, 1 Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977358B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-f200f8649c6a4c20b5df8e9f1d76f86a |
| Source note | uspto-grants-2011_07 |