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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011979Generated: October 30, 2026

4-Pyridinecarboxaldehyde → N-[(E)-pyridin-4-ylmethylideneamino]-3-(trifluoromethoxy)aniline

https://huagongshe.com/reaction/1011979

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PyridinecarboxaldehydeHCID 13389—
Reactant[3-(Trifluoromethoxy)phenyl]hydrazineHCID 5194226—
ProductN-[(E)-pyridin-4-ylmethylideneamino]-3-(trifluoromethoxy)anilineHCID 8735268840%

Reaction Steps

In analogy to the procedure described in Example 167A], 3-(trifluoromethoxy)phenylhydrazine and pyridine-4-carbaldehyde gave the title compound as a light yellow solid (40%). MS: 282.0 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977358B2
Source datasetuspto-grants-2011_07
ORD IDord-2b88fc7a3e454039aeefa2582ad88243
Source noteuspto-grants-2011_07