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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011982Generated: October 29, 2026

2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo- → HCID 67314385, compound

https://huagongshe.com/reaction/1011982

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo-HCID 81242—
ReactantEthyl 3-cyclopropyl-3-oxopropanoateHCID 262979—
ProductHCID 67314385HCID 6731438560%

Reaction Steps

In analogy to the procedure described in Example 160A], 3-cyclopropyl-3-oxo-propionic acid ethyl ester and (1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetyl chloride gave the title compound as a white solid (60%). MS: 342.1 (M−H−).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977358B2
Source datasetuspto-grants-2011_07
ORD IDord-4e7d4f4122b84e6f967142abdbe8c152
Source noteuspto-grants-2011_07