HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(S)-(-)-3-Acetamidopyrrolidine → N-((S)-1-{1-[5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonyl]-piperidin-4-yl}-pyrrolidin-3-yl)-acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (S)-(-)-3-Acetamidopyrrolidine | HCID 7021471 | — |
| Edukt | [5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonyl]-piperidin-4-one | HCID 67314190 | — |
| Produkt | N-((S)-1-{1-[5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonyl]-piperidin-4-yl}-pyrrolidin-3-yl)-acetamide | HCID 57554935 | — |
Reaktionsschritte
The title compound was prepared from 1-[5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonyl]-piperidin-4-one (Example 181B) and (S)—N-pyrrolidin-3-yl-acetamide in direct analogy to the general procedure used in example 129. MS: 504.3 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07977358B2 |
| Quelldatensatz | uspto-grants-2011_07 |
| ORD ID | ord-2287dccea5c1472c8c4326f00a82ec29 |
| Quellennotiz | uspto-grants-2011_07 |