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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1012006Generated: October 30, 2026

[5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonyl]-piperidin-4-one → HCID 57554913, compound

https://huagongshe.com/reaction/1012006

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonyl]-piperidin-4-oneHCID 67314190—
Reactant1107659-80-2HCID 67314332—
ProductHCID 57554913HCID 57554913—

Reaction Steps

The title compound was prepared from 1-[5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonyl]-piperidin-4-one (Example 181B) and (2R,3R)-2-methyl-pyrrolidin-3-ol hydrochloride (example 188A) in direct analogy to the general procedure used in example 129. MS: 477.3 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977358B2
Source datasetuspto-grants-2011_07
ORD IDord-0186666ed75a4ba5a6700189a477520a
Source noteuspto-grants-2011_07