HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carboxylic acid → [5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazol-4-yl]-((3S,4S)-3-methyl-4-pyrrolidin-1-yl-piperidin-1-yl)-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carboxylic acid | HCID 67314593 | — |
| Edukt | (trans)-3-Methyl-4-pyrrolidin-1-yl-piperidine dihydrochloride | HCID 67314766 | — |
| Produkt | [5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazol-4-yl]-((3S,4S)-3-methyl-4-pyrrolidin-1-yl-piperidin-1-yl)-methanone | HCID 57554936 | — |
Reaktionsschritte
The title compound was prepared from 5-cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carboxylic acid (Example 181A) and (trans)-3-methyl-4-pyrrolidin-1-yl-piperidine dihydrochloride (example 195C) in direct analogy to the general procedure used in example 150. MS: 461.3 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07977358B2 |
| Quelldatensatz | uspto-grants-2011_07 |
| ORD ID | ord-f8fad0f541864eb89d333585559009f1 |
| Quellennotiz | uspto-grants-2011_07 |