Hydrochloric Acid → Benzyl 3-(2-amino-6-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-amino}pyrimidin-4-yl)piperidine-1-carboxylate
Reaction equation
[C:44](=[O:45])([OH:46])[O-:47].[CH3:50][CH2:51][OH:52].[ClH:43].[F:25][c:26]1[cH:27][c:28]([NH2:29])[cH:30][cH:31][c:32]1[O:33][c:34]1[c:35]2[c:36]([n:37][cH:38][cH:39]1)[nH:40][cH:41][cH:42]2.[NH2:1][c:2]1[n:3][c:4]([Cl:24])[cH:5][c:6]([CH:8]2[CH2:9][N:10]([C:14](=[O:15])[O:16][CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[CH2:11][CH2:12][CH2:13]2)[n:7]1.[Na+:48].[OH2:49]>>[NH2:1][c:2]1[n:3][c:4]([NH:29][c:28]2[cH:27][c:26]([F:25])[c:32]([O:33][c:34]3[c:35]4[c:36]([n:37][cH:38][cH:39]3)[nH:40][cH:41][cH:42]4)[cH:31][cH:30]2)[cH:5][c:6]([CH:8]2[CH2:9][N:10]([C:14](=[O:15])[O:16][CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[CH2:11][CH2:12][CH2:13]2)[n:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b9fe1c261bb24f5ab9ca53f647e3d6f6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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