HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-fluorobenzoic acid → 4-(2-Chloro-6-fluorobenzamido)-1H-pyrazole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-fluorobenzoic acid | HCID 67947 | — |
| Reactant | HCID 178524954 | HCID 178524954 | — |
| Product | 4-(2-Chloro-6-fluorobenzamido)-1H-pyrazole-5-carboxylic acid | HCID 178524953 | — |
Reaction Steps
The compound was prepared in a manner analogous to 4-(2,6-difluoro-benzoylamino)-1H-pyrazole-3-carboxylic acid (Example 16D), but using 2-chloro-6-fluorobenzoic acid as the starting acid to give 4-(2-chloro-6-fluoro-benzoylamino)-1H-pyrazole-3-carboxylic acid (4.42 g) as a pale blue solid. (LC/MS: Rt 2.35, [M+H]+ 283.94).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977477B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-541d7ec6fa8e4512a1d2b109e7b0dc0a |
| Source note | uspto-grants-2011_07 |