HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178466989, compound → HCID 178466937, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178466989 | HCID 178466989 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178466937 | HCID 178466937 | 88.5% |
Reaction Steps
A mixture of 4-nitro-N-[3-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxy-benzamide (115 mg) and 10% Pd/C (20 mg) in EtOH (10 mL) was stirred under a hydrogen atmosphere for 2 h at r.t. The mixture was filtered through Celite and reduced in vacuo to give the title compound (95 mg). (LC/MS: Rt 2.11, [M+H]+ 423).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977477B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-9b356a45dca04591962481df6e74b721 |
| Source note | uspto-grants-2011_07 |