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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1012148Generated: October 30, 2026

HCID 178466989, compound → HCID 178466937, compound

https://huagongshe.com/reaction/1012148

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178466989HCID 178466989—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 178466937HCID 17846693788.5%

Reaction Steps

A mixture of 4-nitro-N-[3-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxy-benzamide (115 mg) and 10% Pd/C (20 mg) in EtOH (10 mL) was stirred under a hydrogen atmosphere for 2 h at r.t. The mixture was filtered through Celite and reduced in vacuo to give the title compound (95 mg). (LC/MS: Rt 2.11, [M+H]+ 423).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977477B2
Source datasetuspto-grants-2011_07
ORD IDord-9b356a45dca04591962481df6e74b721
Source noteuspto-grants-2011_07